Common Side Effects of Modafinil
Modafinil has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and compared to side effects that occur in another group of people not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common side effects of modafinil included:
- Headaches -- in up to 34 percent of people
- Nausea -- up to 11 percent
- Nervousness -- up to 7 percent
- Runny or stuffy nose -- up to 7 percent
- Back pain -- up to 6 percent
- Diarrhea -- up to 6 percent
- Indigestion or heartburn -- up to 5 percent
- Insomnia -- up to 5 percent (see Provigil and Insomnia)
- Dizziness -- up to 5 percent.
Other common side effects, occurring in 1 to 4 percent of people, included:
- Flu-like symptoms (such as fever and chills)
- Dry mouth (see Provigil and Dry Mouth)
- Loss of appetite
- Sore throat
- Flushing or hot flashes
- Constipation
- Unusual sensations, such as numbness or tingling
- Drowsiness
- Neck stiffness
- Gas
- Mouth sores
- Thirst
- Water retention
- Shakiness (tremor)
- A spinning sensation (vertigo)
- Nosebleeds
- Sweating
- Cold sores or genital herpes
- Vision problems or eye pain
- Changes in taste.
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